Anterior cingulate cortex
Gyrus cinguli, pars anterior
- Acronym: BA32
Definition
The anterior cingulate cortex (ACC) is a region of the medial frontal lobe, encompassing Brodmann's areas 24, 25, and 32. It plays a crucial role in various cognitive and emotional processes, such as emotional regulation, decision-making, autonomic control, and the integration of cognitive and affective information.
Abnormal activity in the ACC has been implicated in various psychiatric and neurological disorders.
References
1. Gasquoine PG. Localization of Function in Anterior Cingulate Cortex: From Psychosurgery to Functional Neuroimaging. Neuroscience and Biobehavioral Reviews. 2013;37(3):340-8. doi:10.1016/j.neubiorev.2013.01.002.
2. Monosov IE, Haber SN, Leuthardt EC, Jezzini A. Anterior Cingulate Cortex and the Control of Dynamic Behavior in Primates. Current Biology : CB. 2020;30(23):R1442-R1454. doi:10.1016/j.cub.2020.10.009.
3. Seamans JK. The Anterior Cingulate Cortex and Event-Based Modulation of Autonomic States. International Review of Neurobiology. 2021;158:135-169. doi:10.1016/bs.irn.2020.11.006.
4. Alexander L, Jelen LA, Mehta MA, Young AH. The anterior cingulate cortex as a key locus of ketamine's antidepressant action. Neurosci Biobehav Rev. 2021 Aug;127:531-554. doi: 10.1016/j.neubiorev.2021.05.003. Epub 2021 May 11. PMID: 33984391.
