Central intermediate substance
Substantia intermedia centralis
Definition
The central intermediate substance consists of gray matter surrounding the central canal of the spinal cord and corresponds to Rexed lamina X. It is divided into dorsal and ventral commissures, located behind and in front of the central canal, respectively. These commissures connect the gray matter of the right and left halves of the spinal cord.
Laterally, the central intermediate substance transitions into the lateral intermediate substance, also known as the base of the posterior horn or lamina VII. This region is situated between the posterior and anterior horns of the spinal gray matter. Together, the central and lateral intermediate substances form the intermediate zone of the spinal cord.
References
Snell, R.S. (2010). ‘Chapter 4: The Spinal Cord and the Ascending and Descending Tracts’, in Clinical Neuroanatomy. (7th ed.) Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, pp. 137-142.
Byrne, J.H. and Dafny, N. ‘Chapter 3: Anatomy of the Spinal Cord. [Content reviewed and revised 07 Oct 2020]. In Neuroanatomy Online, an open-access electronic laboratory for the neurosciences. McGovern Medical School at UTHealth; Accessed 2022 Oct 22. Available from: https://nba.uth.tmc.edu/neuroscience/m/s2/chapter03.html
Brown, A.G. (1982). Review article the dorsal horn of the spinal cord. Quarterly Journal of Experimental Physiology: Translation and Integration, 67(2), pp.193-212. https://doi.org/10.1113/expphysiol.1982.sp002630
Ganapathy, M.K., Reddy, V. and Tadi, P. Neuroanatomy, Spinal Cord Morphology. [Updated 2021 Oct 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545206/
YousufDar, M. 2015. Neuroanatomical structures of spinal cord–A review. International Journal of Livestock Research. 5(7), pp. 11-23. https://doi.org/10.1113/expphysiol.1982.sp002630
