Central intermediate substance
Substantia intermedia centralis
Definition
The central intermediate substance comprises of the gray matter that surrounds the central canal of spinal cord and corresponds with the Rexed lamina X. It can be divided into dorsal and ventral commissures, behind and in front of the central canal, respectively. These commissures interconnect the gray matter of the right and left spinal halves with each other.
The central intermediate substance continues laterally as the lateral intermediate substance (a.k.a. base of posterior horn or lamina VII), which comes to lie between the posterior and anterior horns of the spinal gray matter Together, the central and lateral intermediate substances constitute the intermediate zone of spinal cord.
References
Text written by Muhammad A. Javaid, MD, PhD © 2022 IMAIOS.
Snell, R.S. (2010). ‘Chapter 4: The Spinal Cord and the Ascending and Descending Tracts’, in Clinical Neuroanatomy. (7th ed.) Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, pp. 137-142.
Byrne, J.H. and Dafny, N. ‘Chapter 3: Anatomy of the Spinal Cord. [Content reviewed and revised 07 Oct 2020]. In Neuroanatomy Online, an open-access electronic laboratory for the neurosciences. McGovern Medical School at UTHealth; Accessed 2022 Oct 22. Available from: https://nba.uth.tmc.edu/neuroscience/m/s2/chapter03.html
Brown, A.G. (1982). Review article the dorsal horn of the spinal cord. Quarterly Journal of Experimental Physiology: Translation and Integration, 67(2), pp.193-212. https://doi.org/10.1113/expphysiol.1982.sp002630
Ganapathy, M.K., Reddy, V. and Tadi, P. Neuroanatomy, Spinal Cord Morphology. [Updated 2021 Oct 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545206/
YousufDar, M. 2015. Neuroanatomical structures of spinal cord–A review. International Journal of Livestock Research. 5(7), pp. 11-23. https://doi.org/10.1113/expphysiol.1982.sp002630
