Nervous system
Systema nervosum
Definition
The nervous system is among the most complex and intricate systems in the human body. It comprises specialized cells that detect and process sensory information from within and outside the body. This system coordinates and generates motor responses, often using stored information from past experiences, and transmits these responses to effector organs such as muscles and glands to maintain the body's harmonious functioning.
The nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, which includes the brain and spinal cord, acts as the primary center for processing and integrating nervous information, functioning as the body's command center. The PNS consists of cranial and spinal nerves, along with associated ganglia and plexuses, and serves as the communication network between the CNS and the rest of the body.
The brain and spinal cord are safeguarded by membranes known as meninges and are suspended in cerebrospinal fluid, providing cushioning. These structures are also protected by the skull and the vertebral column.
The core components of the CNS include the cerebral cortex, subcortical nuclei, brainstem, cerebellum, and spinal cord.
The cerebral cortex, characterized by gyri and sulci, is divided into four lobes and is essential for high-level brain functions.
Subcortical structures such as the basal nuclei and thalamus lie beneath the cortex and further process information.
The brainstem, comprising the midbrain, pons, and medulla oblongata, is vital for basic life functions.
The cerebellum, located behind the brainstem, is responsible for balance and coordination.
The spinal cord extends from the brainstem through the vertebral canal, facilitating communication between the brain and the rest of the body.
At the cellular level, the CNS is made up of numerous excitable nerve cells called neurons, supported by specialized tissue known as neuroglia. The system is organized into gray matter, which contains nerve cell bodies and neuroglia, and white matter, composed of nerve fibers (axons) encased in myelin, giving it a white appearance.
The PNS consists of 31 pairs of spinal nerves, each emerging from specific segments of the spinal cord, and 12 pairs of cranial nerves originating from the base of the brain.
Additionally, the autonomic nervous system (ANS) is crucial for the involuntary control of functions such as heart rate, digestion, and glandular activity. It is divided into the sympathetic and parasympathetic systems. The sympathetic system prepares the body for emergency responses, while the parasympathetic system conserves and restores energy.
This overview provides a foundation for understanding the anatomy and key components of the nervous system, ensuring you keep the big picture in mind as you delve deeper into its details.
References
Snell, R.S., 2010. Chapter 1: Introduction and organization of nervous system. In: Clinical Neuroanatomy. 7th ed. Philadelphia: Lippincott Williams & Wilkins, pp. 1-14.
Ludwig, P.E., Reddy, V. and Varacallo, M. Neuroanatomy, Central Nervous System (CNS) [Updated 2022 Oct 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK442010/