Lymphoid organs

Organa lymphoidea

  • Latin synonym: Systema lymphoideum
  • Synonym: Lymphoid system; Lymphatic organs
  • Related terms: Lymphoid system

Definition

Antoine Micheau

Lymphoid organs are specialized structures within the immune system that are involved in the production, maturation, and activation of lymphocytes. They are classified into three main categories:

1. Primary lymphoid organs: These include the thymus and bone marrow, where T and B lymphocytes, respectively, develop and mature independently of antigens.

2. Secondary lymphoid organs: These include lymph nodes, spleen, Peyer's patches, and mucosal-associated lymphoid tissues such as pharyngeal lymphoid ring (the tonsils) and adenoids. SLOs are sites where lymphocytes encounter antigens, leading to their activation and proliferation.

3. Tertiary lymphoid organs (TLOs): These are ectopic lymphoid structures that form in response to chronic inflammation and resemble SLOs in their cellular composition and organization.

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