Spinoperiaqueductal fibers

Fibrae spinoperiaquaeductales

  • Latin synonym: Fibrae spinoperiaqueductales
  • Related terms: Spinoperiaqueductal fibres

Definition

Muhammad A. Javaid

Spinoperiaqueductal fibers are a subset of fibers within the spinomesencephalic tract that specifically terminate in the periaqueductal gray of the midbrain. These fibers are involved in conveying nociceptive (pain) information to the periaqueductal gray, which is a critical structure for modulating pain through descending inhibitory pathways.

Please note that the spinomesencephalic tract is a broader term encompassing all fibers within the tract that terminate in various midbrain structures, including the periaqueductal gray, cuneiform nucleus, superior colliculus, red nucleus, and other mentioned areas. In contrast, spinoperiaqueductal fibers refer exclusively to the portion of the spinomesencephalic that targets the periaqueductal gray specifically, emphasizing its role in pain modulation.

References

  • Kam, P., & Power, I. (2020). Principles of Physiology for the Anaesthetist (4th ed.). CRC Press. https://doi.org/10.1201/9780429288210

  • Loyd DR, Murphy AZ. The role of the periaqueductal gray in the modulation of pain in males and females: are the anatomy and physiology really that different? Neural Plast. 2009;2009:462879. doi: 10.1155/2009/462879