Subserosa of large intestine
Tela subserosa intestini crassi
- Synonym: Subserous layer of large intestine
- Related terms: Subserosa; Subserous layer
Definition
The subserosa of large intestine underlies the serosa and may contain few deposits of adipose tissue.
The subserosa contains varying amounts of adipose tissue, blood vessels, lymphatics, and nerves that supply the outer layers of the intestinal wall. It serves as a supportive layer, anchoring the serosa to the underlying muscular coat while allowing a degree of mobility between these layers.
Clinical correlate
The subserosa acts as a pathway for spread of inflammation and malignant tumours beyond the bowel wall.
References
Standring, S. (2015) Grays Anatomy: The Anatomical Basis of Clinical Practice. 41st edn. London: Churchill Livingstone Elsevier. Chapter 66, Large intestine.
Omole AE, Mandiga P, Kahai P, et al. Anatomy, Abdomen and Pelvis: Large Intestine. [Updated 2025 Apr 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470577/
