Superior occipitofrontal fasciculus
Fasciculus occipitofrontalis superior
- Related terms: Superior occipitofrontal fasciculus; Subcallosal fasciculus
Definition
The superior occipitofrontal fasciculus (a.k.a. superior fronto-occipital fasciculus) is an example of a long association fiber.
In general, association fibers comprise of bundles of white matter fibers that interconnect various distant or adjacent cortical regions within the ‘same’ cerebral hemisphere of the brain. The superior occipitofrontal fasciculus is specifically located deep within the cerebral hemisphere, just lateral to the caudate nucleus. It connects the frontal lobe in front (cranially) with the occipital lobe at the back (caudally).
These association fibers or bundles, including the superior occipitofrontal fasciculus, can lose their myelin sheath in diseases such as multiple sclerosis and other demyelinating diseases, leading to a cognitive decline.
References
Text written by Muhammad A. Javaid, MD, PhD © 2022 IMAIOS.
Snell, R.S. (2010). ‘Chapter 8: The Structure and Functional Localization of the Cerebral Cortex’, in Clinical Neuroanatomy. (7th ed.) Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, pp. 261-262.
Felten, D.L., O'Banion, M.K. and Maida, M.S. (2016). ‘Chapter 13: Telencephalon’, in Netter's Atlas of Neuroscience (3rd ed.), Elsevier Ltd., pp. 295-352. https://doi.org/10.1016/B978-0-323-26511-9.00013-8
