Fundus of stomach

The fundus of stomach is the posterosuperior, dome-shaped left part of stomach, that lies above the level of the cardiac orifice. It is situated beneath the left dome of the diaphragm and forms the uppermost part of the stomach. The fundus commonly contains a gastric air bubble, which is often visible on radiographic imaging.

Histology

The fundus region of stomach contains fundic (oxyntic) glands that are rich in parietal cells, which secrete hydrochloric acid and intrinsic factor, and chief cells, which secrete pepsinogen.

Function

The fundus of stomach serves as a reservoir for swallowed food and air and contributes to gastric digestion through the secretion of acid and digestive enzymes.