Longitudinal cerebral fissure

The longitudinal cerebral fissure is a deep groove that separates the two cerebral hemispheres. It is also known as the median longitudinal fissure, cerebral fissure, or interhemispheric fissure.

The longitudinal cerebral fissure contains a curved strip of meningeal tissue called the falx cerebri. It extends across the entire medial aspect of the cerebral hemispheres, both at the front and rear ends, effectively separating them completely from their upper to lower margins. However, in the middle region of the fissure, the separation is only about half as deep. This is because the hemispheres are joined by a sizable central band of white matter nerve fibers, called the corpus callosum, which runs from side to side, connecting the two hemispheres.