Precommissural fibers

Fibrae precommissurales

  • Latin synonym: Fibrae praecommissurales
  • Related terms: Precommissural fornix; Precommissural fibres

Definition

Muhammad A. Javaid

The precommissural fibres of the fornix are fibres from the columns of the fornix that pass anterior to the anterior commissure. This position distinguishes them from the postcommissural fibres, which curve posterior to the anterior commissure.

According to Senova et al. (2020), the precommissural fornix contains the septohippocampal pathway and also carries projections to the forebrain. The septohippocampal pathway connects the medial septal region with the hippocampus and contributes to the regulation of hippocampal activity, particularly theta oscillations associated with learning, spatial processing and episodic-memory circuits.

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References

  • Senova S, Fomenko A, Gondard E, Lozano AM. Anatomy and function of the fornix in the context of its potential as a therapeutic target. J Neurol Neurosurg Psychiatry. 2020 May;91(5):547-559.