Infrapatellar fat pad

Corpus adiposum infrapatellare

  • Eponym: Fat pad of Hoffa

Definition

Antoine Micheau

The infrapatellar fat pad (IFP; Hoffa's fat pad), is an intracapsular but extrasynovial structure located in the space between the inferior border of the patella, the femoral condyles, the tibial plateau, and the patellar tendon.[1-3]

Anatomically, the infrapatellar fat pad is composed of white adipose tissue organized into lobules, which are defined by thin connective septa. It is richly vascularized and innervated, containing a significant number of blood vessels and nerves.[4-5] The IFP attaches to several structures within the knee, including the inferior patellar pole, the femoral intercondylar notch via the ligamentum mucosum, the proximal patellar tendon, both menisci, and the anterior tibia via meniscotibial ligaments.[2]

The infrapatellar fat pad presents:

  • A central body with a superior vertical cleft

  • Two superior extensions: a lateral superior and a medial superior extension that wrap around the patella, which are visible on MRI and can be identified medially and laterally. These extensions and the dynamic nature of the IFP allow it to deform during knee motion, displacing superiorly and posteriorly during knee flexion.[2-3]

  • A medial and a lateral extension

Histologically, the IFP consists of large adipose lobules near the patellar tendon and smaller lobules in the deeper portions, with the superficial lobules showing significant changes in size during knee flexion and extension.[3][5] This structural arrangement suggests a role in absorbing pressure variations and contributing to knee kinematics.[3][5]

References

1.An Investigation of the Anatomy of the Infrapatellar Fat Pad and Its Possible Involvement in Anterior Pain Syndrome: A Cadaveric Study.Leese J, Davies DC.Journal of Anatomy. 2020;237(1):20-28. doi:10.1111/joa.13177.

2.The Infrapatellar Fat Pad Is a Dynamic and Mobile Structure, Which Deforms During Knee Motion, and Has Proximal Extensions Which Wrap Around the Patella.Stephen JM, Sopher R, Tullie S, et al.Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA. 2018;26(11):3515-3524. doi:10.1007/s00167-018-4943-1.

3.The Characteristics of the Lobular Arrangement Indicate the Dynamic Role Played by the Infrapatellar Fat Pad in Knee Kinematics.Macchi V, Picardi EEE, Fontanella CG, et al.Journal of Anatomy. 2019;235(1):80-87. doi:10.1111/joa.12995.

4.Inflammation of the Infrapatellar Fat Pad.Eymard F, Chevalier X.Joint Bone Spine. 2016;83(4):389-93. doi:10.1016/j.jbspin.2016.02.016.

5.The Infrapatellar Adipose Body: A Histotopographic Study.Macchi V, Porzionato A, Sarasin G, et al.Cells, Tissues, Organs. 2016;201(3):220-31. doi:10.1159/000442876.

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