Nucleus of abducens nerve

Nucleus nervi abducentis

  • Synonym: Abducens nucleus

Definition

Muhammad A. Javaid

The nucleus of abducens nerve functions as a general somatic motor nerve nucleus, responsible for innervating the lateral rectus muscle, which facilitates the abduction of the eyeball.

Location:

It is situated beneath the floor of the fourth ventricle, near the midline, and lies under the facial colliculus.

Afferent neurons:

The nucleus of abducens nerve receives several afferent connections, including:

  • Corticonuclear fibers from both cerebral hemispheres.

  • Tectobulbar fibers originating from the superior colliculus, which connect to the ipsilateral abducens nerve nucleus. These fibers are essential for the supranuclear control of eye movements. The nucleus of abducens nerve is further connected to the contralateral oculomotor nerve nucleus via fibers of the medial longitudinal fasciculus.

  • Inputs from the vestibular nuclei, transmitted through the medial longitudinal fasciculus to reach the abducens, oculomotor, and trochlear nerve nuclei, play a crucial role in mediating vestibulo-ocular reflexes.

Efferent neurons:

  • Efferent fibers from the abducens nerve nucleus innervate the lateral rectus muscle, enabling outward movement (abduction) of the eyeball.

  • As part of supranuclear control mechanisms for eye movements, efferent neurons travel through the medial longitudinal fasciculus to connect with the oculomotor nerve nucleus on the opposite side. This arrangement facilitates horizontal conjugate movements of the eyes by coordinating the action of the ipsilateral lateral rectus muscle and contralateral medial rectus muscle.

References

  • Blumenfeld, H. (2010). ‘Chapter 13: Brainstem II: Eye movements and Pupillary Control’, in Neuroanatomy through clinical cases. (2nd ed.) Sunderland, Mass.: Sinauer Associates, pp. 548-549.

  • Snell, R.S. (2010). ‘Chapter 11: The cranial nerve nuclei and their central connections and distribution’, in Clinical Neuroanatomy. (7th ed.) Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, pp. 344-345.

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